Compile Data Set for Download or QSAR
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Found 110 of affinity data for UniProtKB/TrEMBL: Q64264
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50040177(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044238(CHEMBL63449 | S-(-)-1-(8-Dipropylamino-6,7,8,9-tet...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in CHO-cells (sc)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044237(CHEMBL65274 | R-(+)-1-(8-Dipropylamino-6,7,8,9-tet...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in CHO-cells (sc)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034330((3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  0.400nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186927(US9079895, 19s)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034366(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Affinity DataKi:  0.800nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50407735(CHEMBL2021539)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034368(CHEMBL28313 | Trifluoro-methanesulfonic acid 7-pro...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50342717(4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-meth...)
Affinity DataKi:  3.20nMAssay Description:Ability to displace [125I]iodosulpiride from 5-hydroxytryptamine 1A receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  3.70nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50280297(1,1-Dioxo-2-[(1S,2S)-2-(4-pyrimidin-2-yl-piperazin...)
Affinity DataKi:  8.70nMAssay Description:Compound was tested for binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50407737(CHEMBL2021538)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataKi:  12nMAssay Description:Compound was tested for binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50407734(CHEMBL2021524)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50078561(CHEMBL1204203 | CHEMBL416266 | Ethanesulfonic acid...)
Affinity DataKi:  27nMAssay Description:Binding affinity of the compound towards 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50280296(1,1-Dioxo-2-[(1R,2S)-2-(4-pyrimidin-2-yl-piperazin...)
Affinity DataKi:  44nMAssay Description:Compound was tested for binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034324((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Affinity DataKi:  55nMAssay Description:Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50040166(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Affinity DataKi:  100nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186937(US9079895, 25s)
Affinity DataKi:  174nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034365(CHEMBL554220 | Trifluoro-methanesulfonic acid (R)-...)
Affinity DataKi:  222nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi: >333nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186936(US9079895, 24s)
Affinity DataKi:  371nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186932(US9079895, 22r)
Affinity DataKi:  384nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  385nMAssay Description:Binding affinity of the compound at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)
Affinity DataKi: >500nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor receptor, using [3H]5-HT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50070518((R)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-...)
Affinity DataKi:  525nMAssay Description:In vivo binding affinity was evaluated against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186957(US9079895, 61)
Affinity DataKi:  540nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186935(US9079895, 23s)
Affinity DataKi:  545nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186953(US9079895, 60)
Affinity DataKi:  592nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186962(US9079895, 64)
Affinity DataKi:  644nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50070514((S)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-...)
Affinity DataKi:  991nMAssay Description:In vivo binding affinity was evaluated against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  1.00E+3nMAssay Description:Compound was evaluated for binding affinity against 5-hydroxytryptamine 1A receptor using radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50069907(1-benzyl-4-(3-hydroxyphenyl)piperazine | 3-(4-Benz...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50014154(2-(5-Methyl-1H-imidazol-4-ylmethyl)-4-phenyl-thiaz...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determined by using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50407736(CHEMBL2021525)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186934(US9079895, 22s)
Affinity DataKi:  1.39E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186938(US9079895, 25r)
Affinity DataKi:  1.47E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Affinity DataKi:  1.78E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186933(US9079895, 23r)
Affinity DataKi:  1.85E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186924(US9079895, 16r)
Affinity DataKi:  2.30E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186923(US9079895, 15r)
Affinity DataKi:  2.88E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against serotonergic 5-HT1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  3.71E+3nMAssay Description:Compound was tested for binding affinity using [3H]8-OH-DPAT against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50057837((5aS,11bS)-4,5,5a,6,7,11b-Hexahydro-1-thia-5-aza-c...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186961(US9079895, 63)
Affinity DataKi:  5.02E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186968(US9079895, 70)
Affinity DataKi:  6.37E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50408197(CHEMBL91605)
Affinity DataKi:  6.50E+3nMAssay Description:The compound's binding affinity against 5-hydroxytryptamine 1A receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM186960(US9079895, 62)
Affinity DataKi:  6.59E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50408236(CHEMBL420620)
Affinity DataKi:  6.70E+3nMAssay Description:The compound's binding affinity against 5-hydroxytryptamine 1A receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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